Impact of atrial fibrillation on outcome of percutaneous mitral valve repair (PMVR) procedure

Abstract Background Limited evidence exists regarding the impact of atrial fibrillation (AF) on outcomes after percutaneous mitral valve repair (PMVR). The aim present study was to compare 1-year clinical following PMVR in patients with and without AF. Methods 426 for severe MR were included COburg MItraclip (COMI) registry between 2016 2021. Patients divided into an AF group (group A, n=284) a non-AF B, n=142). Clinical profiles, procedure characteristics follow-up compared two groups. Results older (79.3±6.3 [AF] vs. 77.8±8 years [non-AF], p=0.03), had higher N-terminal B-type natriuretic peptide levels (NT-pro BNP: 5675±5544.2 vs 8516±11184.5, p=0.004), more often coronary artery disease (62% 38%, p=0.03) lower stroke risk (CHA2DS2-VASc score: 4.6±1.2 4.9±1.3, p=0.01). There no significant differences groups regard gender, logistic Euroscore or prevalence chronic heart failure, hypertension, diabetes mellitus regurgitation. Acute procedural success (post-procedural 2. MR, 95.1% 94.4%; p=0.76) procedure-related major complications similar. MACCE (death, MI, stroke, bleeding), health-related quality life improvement. Conclusion In regurgitation who underwent PMVR, is common appears not have relevant negative outcome at 1 year sinus rhythm. Funding Acknowledgement Type funding sources: None.